Chosen Solution

I have 2 Epson Home Cinema 1060 that show no signs of life (No Lights). Both have the same issue. The motherboards are dead. I swap with a working board and it works great.

Any ideas where to start on diagnosing the board? I can’t find a fuse on this board.

Here is a photo of a working board.

KDammen  looks like the power supply is actually shown bottom right in your picture. We would need to see more of that. The fuse will be in/on the power supply. That were I would suggest you start. Post some more picture of the power supply connectors and the pinouts as show on the board etc. so we can help you further. The image of your main board is good but to global to properly identify components. Try to post multiple areas of that with your question as well. For now, the power supply area on the right would be my prime suspect for finding the issue.